UF1 PCR thermal cycler

The UF1 thermal cycler uses a recyclable consumable with tubes for assay samples. The reaction is monitored using fluorescence detection. Sample plates are 24- or 96-well, are interchangeable, and use standard pitches for automated handling.

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Thermal cyclers raise and lower the temperature in PCR, breaking the DNA strands apart and promoting DNA replication. These traditionally use a heat exchange block to warm and cool DNA samples in plastic tubes or microtitre plates, but this can result in slow and uneven temperature changes, and exact temperature control is vital for fast and efficient DNA amplification and accurate and consistent results.

The UF1 thermal cycler uses a low-cost single-use, recyclable consumable that combines the microtitre plate, heat exchange block, and attached heaters. This puts the DNA samples in direct contact with the heating element, resulting in rapid and controlled temperature changes, at up to seven cycles per minute. The disposable plate is simple to use, decreasing user error, eliminates the time and cost involved in cleaning, as well as reduces the risk of cross-sample contamination.

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PCR, thermal cycler, thermal cycling, DNA, heat exchange, DNA replication, microtitre